Prenatal exposure to nanoparticles may adversely affect sperm production in offspring, according to a Danish study on mice.
Scientists from the National Research Centre for the Working Environment and the Technical University of Denmark exposed mice to titanium dioxide and carbon black. Although maternal exposure did not have a statistically significant effect on daily sperm production in the first generation, titanium dioxide exposure “tended to reduce sperm counts” write the authors in a paper published in Reproductive Toxicology. Mice whose fathers had been prenatally exposed to carbon black also had lower sperm production.
Meanwhile, an Indian study on mice suggests a link between daily oral exposure to silver nanoparticles and weight loss. Scientists from Utter Pradesh used transmission electron microscopy to reveal that the nanoparticles may have damaged cells in the intestine as well as intestinal glands. The study is published in Toxicology Mechanisms and Methods.